Scientific studies
Below is a list of some specific third party studies relating to the individual components used in Sirtlife sirtuin supplements:
Polydatin – Scientific studies
- Polydatin-induced cell apoptosis and cell cycle arrest are potentiated by Janus kinase 2 inhibition in leukemia cells
- Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest
- Polytadin attenuates diet-induced nonalcoholic steatohepatitis and fibrosis in mice
- Anti-inflammatory effect of resveratrol and polydatin by in vitro IL-17 modulation
- Polydatin inhibits hepatocellular carcinoma via the AKT/STAT3‑FOXO1 signaling pathway
- Polydatin suppresses proliferation and metastasis of non-small cell lung cancer cells by inhibiting NLRP3 inflammasome activation via NF-κB pathway
- Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest
- Protective Effects of Polydatin Against Dementia-Related Disorders
- Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway
- Polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9)
- The antiviral effects of polydatin and resveratrol
- Resveratrol Inhibits Enterovirus 71 Replication and Pro-Inflammatory Cytokine Secretion in Rhabdosarcoma Cells through Blocking IKKs/NF-κB Signaling Pathway
- Polygonum cuspidatum and its active components inhibit replication of the influenza virus through toll-like receptor 9-induced interferon beta expression
- New intriguing possibility for prevention of coronavirus pneumonitis: Natural purified polyphenols
- Active neuraminidase constituents of Polygonum cuspidatum against influenza A(H1N1) influenza virus
- Natural and nature-inspired stilbenoids as antiviral agents
- Antiviral Activity of Resveratrol against Human and Animal Viruses
Pterostilbene – Scientific studies
- Effect of Pterostilbene on hepatic key enzymes of glucose metabolism in streptozotocin and nicotinamide-induced diabetic rats
- Pterostilbene Protects Cochlea from Ototoxicity in Streptozotocin-Induced Diabetic Rats by Inhibiting the Apoptosis
- Study Suggests Pterostilbene Offers Diabetes Relief
- Pterostilbene alleviates diabetic nephropathy in experimental diabetic rats; inhibition of aldose reductase and advanced glycation end products formation
- Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids
- Pterostilbene Ameliorates Streptozotocin-Induced Diabetes through Enhancing Antioxidant Signaling Pathways Mediated by Nrf2
- Pterostilbene Prevents Early Diabetic Retinopathy Alterations in a Rabbit Experimental Model
- Pterostilbene complexed with cyclodextrin exerts antimicrobial and anti-inflammatory effects
Onochiol – Scientific studies
- Neuro-Modulating Effects of Honokiol: A Review
- Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent
- Honokiol: a novel natural agent for cancer prevention and therapy
- Honokiol: A potent chemotherapy candidate for human colorectal carcinoma
- Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABAA receptor in mice
- Neuro-Modulating Effects of Honokiol: A Review
- Antidepressant-like effects of mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents
- Honokiol bis-dichloroacetate (Honokiol DCA) demonstrates activity in vemurafenib-resistant melanoma in vivo.
- Benefits of ellagic acid from grapes and pomegranates against colorectal cancer
- Ellagic Acid and Its Role in Chronic Diseases
Sirt500 Plus is in the protocol of Prof. Ricordi former Director in Miami (Florida) of the Diabetes Research Institute (DRI) and Cell Transplant Center.
Related articles
- AGING: INEVITABLE BUT PARADOXICALLY MANAGEABLE PROCESS
- LONGEVITY: caloric restriction (CR) and the role of sirtuins
- TELOMERASE: the enzyme that turns back the hands of time
- POLYPHENOLS: anti-aging and reverse-aging role by reactivating sirtuins le sirtuine
- RESVERATROL: how to take it to increase our longevity
- BIOLOGICAL AGE: a test to check your biological age.