€ 0.00

No products in the cart.

Free 24-hour shipping in Switzerland for orders over 70€ /Chf - Secure payment method with Credit/Debit Card (PayPal)

€ 0.00

No products in the cart.


Sirtuins and calorie restriction

It has been shown that the only elixir for long life and longevity is caloric restriction and fitness, the only two conditions that can regulate the activation of sirtuins. Sirtuins are enzymes with extraordinary abilities, primarily that of reducing all age-related degenerative processes by a rewind-like mechanism.

In 1935 a group of researchers at Corner University demonstrated how the longest-lived mice followed a low-calorie diet (with 30 to 40 per cent fewer calories, they managed to live 50 per cent longer than their peers who ate in the range of standard caloric amounts). After autopsy, no degenerative diseases were found in 50 per cent of the long-lived mice, so their death was due to natural causes such as aging.

sirtuins and calorie restriction

Sirtuins and calorie restriction, telomeres

Due to its anti-inflammatory and antioxidant effects, sirtuin activation can be implicated in all processes related to both cutaneous and organic ageing and therefore used to prevent chronological ageing and related diseases, such as neurodegenerative diseases (e.g. Alzheimer‘s disease and Parkinson’s disease).

Activation of SIRT1 contributes to the preservation of telomere length, counteracting the progressive shortening typical of the physiological ageing process. Science has recently focused on the development of so-called STACKs (sirtuin-activating compounds), i.e. compounds capable of directly activating sirtuins by mimicking the beneficial effects of caloric restriction and fitness, which for many reasons are not always feasible.

Sirtuins and calorie restriction, a preventive strategy to ensure longevity and well-being without chronic and autoimmune diseases by mimicking calorie restriction with natural polyphenol-based foods and supplements.

Editorial Staff SIRT500 – The Fountain of Youth

broken clouds
4.2 ° C
6.3 °
3.1 °
91 %
75 %
4 °
7 °
12 °
11 °
9 °


SIRTUINS AND BENEFITS: a fit and healthy summer

Sirtuins and benefits Sirtuins are proteins naturally produced by our bodies in large quantities until around the age of 35, when they inexorably begin to...

PERFECT TAN: stimulate it with foods rich in polyphenols and antioxidants

Perfect tan First of all, it is good to remember that exposure to the sun is beneficial and regenerating if done in moderation and with...

SEMAGLUTIDE AND SLIMMING: losing weight quickly as a ‘side effect’

Semaglutide and slimming Conceived, researched and already used as a drug against diabetes, Semaglutide is literally flying off the shelves halfway around the world because...

Ashwagandha plant youth tonic, health and healthy longevity

Ashwagandha plant, what is it? The Ashwaganda plant is a member of the solanaceae and is commonly known as Indian ginseng or by its scientific...

SPEEDING UP METABOLISM: the solution to get through the swimming costume test

Speeding up metabolism The summer season is just around the corner and inevitably the swimming costume test confronts us with the many extra inches of...