What’s in SIRT500 Plus

Sirt500 Plus is a natural food supplement consisting of sirtuin-activating polyphenols and minerals.

Its components are pure and of the highest quality. Extracted using solvent-free procedures only, they are present in Sirt500 Plus in a very high concentration, considerably higher than in other supplements available on the market (*).
Sirt500 Plus contains various polyphenols which activate the sirtuins and are therefore able to stimulate cell rejuvenation and support the immune system during aging, as well as various minerals.


    Ellagic acid is a natural phenolic antioxidant. It has antioxidant, antithrombotic and anti-allergic, vaso-protective and gastro-protective properties.
    Onochiol has been shown to have anti-inflammatory and protective properties. It has preventive effects, especially on the cells of the body. It is also able to reduce the accumulation of body fat.
    Polydatin is a member of the class of imbalances in the polyphenol family. It has antioxidant, anti-inflammatory, anti-aging and anti-aggregant activities.
    Pterostilbene reduces fat accumulation, has protective and anti-inflammatory properties, and supports the immune system by performing preventive activities.

Polyphenols are substances contained in food, mainly in vegetables. They are found mainly in fruit, vegetables, red wine, green tea, chocolate, coffee and olive oil. Polyphenols are substances now known to science and medicine for their proven anti-inflammatory, antioxidant and anti-platelet effects on the body. They are therefore an important element of defence.


  • ZINC
    Zinc is one of the enzyme complexes required for the proper functioning of hormones, insulin, sex hormones and growth hormone. It is an essential mineral for our bodies.
    Selenium is a highly effective antioxidant. It counteracts cellular oxidative stress, has a preventive effect, protects the thyroid and ensures it functions properly, and the skin.
    Chrome regulates insulin levels, a key hormone in the body that influences fat and glucose control.

The table shows what Sirt500 Plus contains and what volume of selected fish, fruit and vegetables you should consume each day to get the amount of protective substances contained in Sirt500 Plus: